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ATAI Life Sciences Reports Positive Phase 2b Results

Atai Life Sciences (NASDAQ: ATAI) has reported its financial results for the second quarter of 2025, revealing significant developments in its pipeline of psychedelic-based therapies. The company's planned strategic combination with Beckley Psytech is expected to solidify its position as a global leader in transformative, psychedelic-based mental health therapies.

The topline data from the core, blinded stage of the phase 2b clinical trial of BPL-003 (intranasal mebufotenin benzoate), aimed at treating patients with treatment-resistant depression (TRD), has yielded positive results. BPL-003 met its primary and all key secondary endpoints, demonstrating rapid, robust, and durable antidepressant effects for up to 8 weeks with a single dose.

Furthermore, Atai reported a $23.6 million increase in cash, cash equivalents, and short-term securities as of June 30, 2025, compared to the previous period. This increase was primarily attributed to $89.2 million in net proceeds from equity issuances and $3.9 million in proceeds from the sale of equity holdings.

The company expects its cash, cash equivalents, short-term securities, public equity holdings, and digital assets to fund operations for the combined company into the second half of 2027. Additionally, Atai's research and development (R&D) expenses for the three months ended June 30, 2025, decreased by $1.5 million compared to the same period the prior year, primarily due to decreases in personnel-related expenses and consulting services.

Atai's general and administrative (G&A) expenses for the same period increased by $1.5 million, primarily due to increased legal and professional service expenses associated with the planned strategic combination with Beckley Psytech and the process to move the corporate domicile to the U.S.

The company's net loss attributable to stockholders for the three months ended June 30, 2025, was $27.7 million, significantly lower than the $57.3 million reported for the same period in 2024.

The ongoing clinical developments and positive financial outlook underscore Atai's commitment to advancing its mission of developing highly effective mental health treatments. The company's pipeline, which includes BPL-003, VLS-01, and EMP-01, all in phase 2 clinical development, aims to address the complex nature of mental health and provide commercially scalable interventional psychiatry therapies.

These financial and clinical advancements position Atai Life Sciences as a key player in the evolving landscape of psychedelic-based mental health therapies, with a focus on delivering long-term value for both patients and shareholders. As a result of these announcements, the company's shares have moved -1.94% on the market, and are now trading at a price of $4.05. For more information, read the company's full 8-K submission here.

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