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Investing Insights – Ionis Pharmaceuticals Stock Analysis

Now trading at a price of $42.65, Ionis Pharmaceuticals has moved -1.0% so far today.

Ionis Pharmaceuticals returned losses of -7.6% last year, with its stock price reaching a high of $50.43 and a low of $23.95. Over the same period, the stock underperformed the S&P 500 index by -24.3%. AThe company's 50-day average price was $40.18. Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. Based in Carlsbad, CA, the Mid-Cap Health Care company has 1,069 full time employees. Ionis Pharmaceuticals has not offered a dividend during the last year.

The Business Is Unprofitable and Its Balance Sheet Is Highly Leveraged:

2019 2020 2021 2022 2023 2024
Revenue (k) $1,122,599 $729,264 $810,456 $587,367 $787,647 $705,138
Operating Margins 33% -24% -4% -70% -45% -67%
Net Margins 25% -61% -4% -46% -47% -64%
Net Income (k) $278,143 -$444,263 -$28,597 -$269,722 -$366,286 -$453,897
Net Interest Expense (k) $12,440 $9,510 $9,349 $8,122 $12,660 $16,994
Depreciation & Amort. (k) $12,540 $13,365 $15,487 $14,328 $10,292 $9,614
Diluted Shares (k) 153,303 139,612 160,340 141,848 143,190 149,514
Earnings Per Share $1.9 -$3.18 -$0.2 -$1.9 -$2.56 -$3.04
EPS Growth n/a -267.37% 93.71% -850.0% -34.74% -18.75%
Avg. Price $64.97 $54.17 $40.86 $35.3 $50.59 $43.1
P/E Ratio 32.48 -17.03 -204.3 -18.58 -19.76 -14.18
Free Cash Flow (k) $314,722 $772 $18,844 -$290,091 -$331,318 -$546,227
CAPEX (k) $30,905 $35,120 $11,955 $15,721 $23,805 $45,280
EV / EBITDA 24.03 -48.41 -336.5 -14.95 -23.7 -15.67
Total Debt (k) $785,500 $539,112 $59,713 $1,194,233 $1,308,360 $1,253,062
Current Ratio 9.97 3.56 9.75 7.07 5.9 8.47

Ionis Pharmaceuticals has declining EPS growth, negative cash flows, and High Levels of Debt. On the other hand, the company has an excellent current ratio of 8.47 working in its favor. Furthermore, Ionis Pharmaceuticals has declining revenues and increasing reinvestment in the business.

Ionis Pharmaceuticals does not have a meaningful trailing P/E ratio since its earnings per share are negative. Its forward EPS guidance is negative too, at $-3.74. The average P/E ratio for the Health Care sector is 22.94. Furthermore, Ionis Pharmaceuticals is likely overvalued compared to the book value of its equity, since its P/B ratio of 10.75 is higher than the sector average of 3.19.

Ionis Pharmaceuticals Has an Average Rating of Buy:

The 26 analysts following Ionis Pharmaceuticals have set target prices ranging from $38.0 to $83.0 per share, for an average of $58.23 with a buy rating. The company is trading -26.8% away from its average target price, indicating that there is an analyst consensus of strong upside potential.

Ionis Pharmaceuticals has an above average percentage of its shares sold short because 9.6% of the company's shares are sold short. Institutions own 107.8% of the company's shares, and the insider ownership rate stands at 0.78%, suggesting a small amount of insider investors. The largest shareholder is FMR, LLC, whose 15% stake in the company is worth $1,007,119,436.

The above analysis is intended for educational purposes only and was performed on the basis of publicly available data. It is not to be construed as a recommendation to buy or sell any security. Any buy, sell, or other recommendations mentioned in the article are direct quotations of consensus recommendations from the analysts covering the stock, and do not represent the opinions of Market Inference or its writers. Past performance, accounting data, and inferences about market position and corporate valuation are not reliable indicators of future price movements. Market Inference does not provide financial advice. Investors should conduct their own review and analysis of any company of interest before making an investment decision.

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